Symbol Name ID |
Smad3
SMAD family member 3 MGI:1201674 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Human Phenotypes | Cystocele |
Renal neoplasm |
Disease(s) Associated with SMAD3 | ||
Loeys-Dietz syndrome 3 | ||
Lynch syndrome |
Mouse Phenotypes | renal/urinary system phenotype |
decreased renal tubule apoptosis |
renal tubular necrosis |
decreased susceptibility to kidney reperfusion injury |
increased susceptibility to kidney reperfusion injury |
tubulointerstitial nephritis |
abnormal renal glomerulus basement membrane thickness |
abnormal mesangial matrix morphology |
abnormal kidney epithelium morphology |
renal interstitial fibrosis |
decreased kidney weight |
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Availability | Mouse Genotype | |||||||||||
Smad3tm1Cxd/Smad3tm1Cxd | * | |||||||||||
Smad3tm1Par/Smad3tm1Par | ||||||||||||
Smad3tm1Sche/Smad3tm1Sche |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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